The risk goes beyond just grapefruit. Here, four foods that don’t mix with certain medications.

We’ve reported on the rising incidence of potentially dangerous drug interactions with grapefruit (and other citrus fruits such as Seville oranges and limes.) In fact, experts have warned that grapefruit juice can have serious interactions with more than 85 different drugs, and it can create an overdose effect if consumed by people using cholesterol lowering statins, antibiotics, calcium channel blockers and more.

“Taking one tablet with a glass of grapefruit juice is like taking 20 tablets with a glass of water,” David Bailey, a clinical pharmacologist at the Lawson Health Research Institute in London, Ontario, who discovered the interaction over 20 years ago, told CBC. “This is unintentional overdosing. So it’s not surprising that these levels go from what we call therapeutic to toxic.”

But the risk goes beyond just grapefruit. Here are some other foods that don’t mix with certain medications:

Black licorice can increase toxicity for those taking Lanoxin, which treats congestive heart failure as well as heart rhythm disorders. It can also cause certain diuretics and blood pressure drugs to become less effective, according to the U.S Food and Drug Administration.

The calcium in dairy foods or from supplements can interact with the absorption of thyroid medicine, as well as antibiotics like levofloxacin and ciprofloxicin.

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Lisa Lagace