Study shows new promise for hypertension drug
The latest issue of the New England Journal of Medicine contains some encouraging results from the Canadian-led, multinational HOPE Study (Heart Outcomes Prevention Evaluation). HOPE, conducted over a four and a half year period, involved more than 9,500 patients worldwide, with more than 60 percent of the patients from Canada.
According to the authors, the study showed that treatment with the anti-hypertensive medication ramipril reduced the risk of cardiovascular events, including heart attacks and strokes, and mortality by 22 per cent, in high-risk patients. Ramipril also reduced the risk of cardiovascular death by 25 per cent, non-fatal heart attack by 20 per cent, and non-fatal stroke by 32 per cent. The results of the HOPE study also showed a 31 per cent reduction in the risk of onset of type II diabetes.